neuroscience of anything and everything

How can a brain stay solid?

2011-11-15T03:17:00.000-08:00

Hi all,
Yesterday I was watching an episode named CSI. There I remember seeing a scene wherein there is an accident happening which was actually a murder and there is a brain been fallen off which does not belong to the person who has died in accident. I am just wondering if a human brain actually stay solid without fixing. If yes how is that it is solid?Even if this happens in low temperature climatic places.. though here in this serial it is in Arizona state in Las Vegas, which is hot place I think also it does not have any muscle like structure in it and there is no bone other than the cranium which surrounds it. There is another episode which says a person killed by inserting a sharp pen . Even if the person is damn old still the cranium is not so easy to allow sharp insertion into the brain to have it damaged... I don't know how much of these episodes is practical.

the attractive black hole and universe a fully evolution human like form

2011-09-03T06:50:00.000-07:00

Today let me call "|my blog day". This is my second consecutive post I am posting from the radiant brain of light with unknown source or from source of dust illuminated to become a thought paves way and comes out as a star or a post here :)
http://www.ted.com/talks/janna_levin_the_sound_the_universe_makes.html.

This talk made me feel universe is a human . Well not with a skin of epithelial cells bundling the bone and muscles and etc etc. Imagine a human made of light a brain of light bundled with a dark space here can be called a drum since a drum is made of skin and hides elongated , fitted and beaten with a stick or hand to produce sound. What is this black hole? Well Human eye:) What ? Yes when I happen to see this talk and see my ted profile picture. I concluded this that the human named universe has a compound eyes with simple eye resolution and characteristic. I still remember Prof Mike Land, University of Sussex, who took the eyes and its resolution in my course saying if you wanna build a compound eye with a simple eye resolution you need a size of the sun may be :) So this universe has different types of cell named stars and sees using black holes but how does it think?

Though I have posted my comment in the talk let me post the same questions here.
My point is what the speaker is actually looking at is the big bang sound to be recorded which happend in the past. What the big bang sound may actually do in the near future? is there any other big sounds predicted apart from the big bang done in this milky way or the black holes drumming the space ? How about the central draw the universe possess . Is there any sucking the air using a straw noise recorded from the universe? the craters the space possesses is the black holes and the path it takes through the white light of stars. Is there a pour of stars somewhere born from dust recorded what we can co relate to as something like a waterfall. is there any movement prediction of these stars walking along the drum or space? what I call it "the locomotion of the universe". Why is universe behaving like a human employed to some firm or organisation working and what is its pay or return for its working?

:) In all the hindu philosophies this universe is called Brahman or brahmi or indra or Shiva or Visvarupa or Brahmam:) so may be if yu read this first and tune your brain into this I think the topic science from the Thaitriya upanishad can be understood better:)

the flowery tale

2011-09-03T05:33:00.000-07:00

http://www.ted.com/talks/jonathan_drori_the_beautiful_tricks_of_flowers.html

Well the flower story begins here.

One of the most fascinating video I have ever come across is this video in TED.com.

the intelligence system used by the flowers is quite stunning. This video actually made me think that the animal brain is far more inferior than the plant system. I still wonder where the plants have the brain to think and do these things. But ah ah the insect or any animal brain is superior in movement and is kinetic while the plant has the potential to do its job static . This is what I call the real boss in the world. It sits in one place and commands the whole world to work for it and pays us salary which is called the food.

The static illusions and dormant observers get their job(pollination) helps us to learn and apply in the advance intelligence system.
How is that the plant creates or develops its flower based on insect sensory system? And Vice versa.
What made the total flaw system of insect pollination pushed into absolute method of pollination of plants. (may be China learnt this system quite well and that's why there is static potential of rise in economy seen by mere numbers like what a flower does releasing millions of its pollen and deceiving the insect to lay eggs in it while the in just a under employment of drinking nectar?On the other hand India struggling to unite and drive its people towards rise in economy though it is equally potent but is innocent and does not actually know how to deceive just like a plant does? ) This thought makes me smile from economy point of view its a shame .
I see the human brain s most attractive flowers such as rose, lily, jasmine are more sensual and emotional attached to the most evolved brain function such as cognition and perception and visual patterns done by your brain may be correlates the flowers appearance? I mean you like rose because your visual brain makes similar patterns in case of pleasant emotions and when you give your emotion a color ends up into rose and when you give your mood a smell it ends up into jasmine?
I see a far more potent plant sensory system than animal yet to be discovered and has anyone shed their light as how a plant actually makes these flowers so purposefully and knowledgeably. I am sure something in them does literature survey though it takes time which we call it evolution but is successful.

Science in thaitriya upanishad or thaitriya upanishad is one among the fundamental science

2011-09-02T07:31:00.000-07:00

transformation of thought to blog

Hi all,
After a very long time, I feel Its time for me to post a new perspective of self.

according to thaitriya upanishad, Brahman or the eternal bliss (in simple term) defines everything. That is you are made of your body and soul.. before arguing into what is body and soul, lets get into wat body and soul is made of from this upanishad. It says"you are made of food, prana, thought and bliss which is in sanskrit annamaya, pranamaya, manonmaya and ananthamaya kosas". food is all the living degradable substance the chemistry and biology, prana the organo- inorganic chemistry which is filled in the confined space of earth to be used by every degradable biological system, we can even call it the food(anna) is the food of prana and prana is locked in anna and is consumed by the anna, you are the food and you are created in food, you consume food and ultimately you are consumed by the food, a highly worldly substance yet it is fundamental.

Next, prana, the first involuntary function of your body divided into prana, apana, vyana, udhana and samana which is the inorganic chemistry of the basic biology(food) the vital energies or reactions such as respiration, digestion, excretion, secretion, circulation etc while samana is the ultimate energy needed by the body to realize its soul to the brahman or eternal bliss which is seen during transformation time (exit from the world).

Manonmaya kosa is highly simple yet complex. Here is where the actual top to down concept of neuroscience begins to shed its light. this manonmaya means the thought process attached to drive involuntarily activities such as prana(as a whole) and ana (food) which is the basic matter or the workers. Here we see how the food {physical matter in the brain and the inorganic chemistry or the involuntary activities going on in the brain actually co ordinates itself tuning into environmental and other external factors registers or drives using thought (can be called memory, learning, neuronal firing etc)} to carry the system for its survival in this world. According to Bhagavad gita mind is the chariot driven by senses as horses and goes on with respect to the horses though you still have the rope to control it yet you are new to drive it and it comes through deligent practice to control it and drive it.

Anandamaya kosa is eternal bliss . What is that ? It is where the act of free will, comes into action. Then ? It is where the sporadic nature of the system itself is seen. Then? It is where spontaneity plays a role. Then? It is where knowledge about researching your system paves way to understand you. What? Yes knowledge about you is act of inert understanding , tracking down the activities going on inside you. You can think about whats going on around you and the sensual things around you but you fail to track the day to day activities you do. You try to know it again externally using methods such as science to explore the world of you observed by others, like you only know eyes and its function from books and methods to understand eyes is using animal or what not something other than you . you don't diagnose anything, the trained physician puts his efforts and mind to observe you. This is the first step in knowledge but we stand in this basic. Unless or until our system shows any symptom we are least bothered about what it does except thirst, hunger etc and bothered more about the senses and sensual reactions such as anger, praise, comparison etc. We never think like now where are we seeing? Why is that we are seeing. What is actually meant by seeing? When we see what is happening? We fail to attach the thought process of every action done by us. If we attach we see how complex we are and we try to understand ourselves not just philosophically but practically too. This approach is done only for rare occasions by us psychological affect we have due to stress or anything. Then we think why the hell are we focusing on that and try to recover or analyse but fail to analyse each and everything we do. Now the act of typing is the act of spontaneity, the act of free will driven by the anandamaya kosa of me(physical) to the manonmaya kosa- the thought, which iniitates the involuntary prana to dedicate and supply energy to my anna or food which is my physical brain. This thought though prevalent regardless of space, time and confinement that is me is now being initiated by the unconfined, time independent, space independent knowledge or Brahman (being called). The knowledge takes a form called thought strikes me (the physical form) is now transformed into words and letter and sentences and confined meaning here in this blog. But yes again this thought about me, what I do or think and what is self is one but can be understood in infinite forms. That is why the knowledge is one but its hands to understand(can be called guaniyn) is infinity. "One in many and many in one" you are the source and you alone is evolutionarily blessed to express yourself about the knowledge or self(can be called brahman here) tuned by your thoughts like a radio tuning the frequency it chooses.

These things going on in my mind expressed here is initiated by the act of trying excavate what death is or transformation is . As I mentioned before, to follow something is basic and researching on it is the next step, I tried to follow the path of harmonious way to die combining the mind and body, concentrating on the factors usually seen in transformation or death here. I figured that two things in me (consciously) is functioning in confining me into the space called me. they are the breath and the next is the current or energy between your eyebrows activating the upper lid of your eyes to function rapidly and not letting you to concentrate on your temple . My prana of live energy is attached to my anna or my eyebrow point call it the pineal gland (may be) narrows my path of thought or manonmaya, to think below that energy and functions normally that is external conscious and normal day to day activity done unconsciously, fails to see the space around the thought (above this energy force physically above the pineal gland) or you which is infinite consciousness of self or brahman.

People, you may call it philosophy preached, but I see this post as the actual "Philosophy of Doctorate of basic science" here.

immune cells in long term automatic memory :)

2011-02-18T09:15:00.000-08:00

Hi all,

new post with some proof related to it

the immune system is the most involuntary memory system , the brains glial cells, astrocytes are the immune cells to brain, why cant they be used for memory consolidation and reconsolidation process? and be used for amnesic patients?

we have a proof that glial cells certainly plays a role in short term memory(see below) why not long term and self initiating memory without learning i mean spontaneous memory?

Role of Glia cells in the formation of memory in the brain

Charles Ross, Shirley Redpath

(Submitted on 18 May 2009)

We build on progress in understanding the role of glia cells in building the initial networks in the foetal brain. This has led us to make three significant postulates. Short term memory results from glia cells forming speculative links directly and solely as a result of neural activity generated by life experiences. These temporary 'glia bridges' create long term memory by stimulating the growth of axons, dendrites and synapses and providing the pathways enabling permanent neural structures to be created. Problem solving, idea creation and memory maintenance results from this fundamental algorithm for how the brain generates new links.

Comments:	5 pages
Subjects:	Neurons and Cognition (q-bio.NC)
Cite as:	arXiv:0905.2836v1 [q-bio.NC]

school questions

2011-02-03T23:42:00.000-08:00

Hi all,
I am back with some shooters which is actually school age questions though :)
When I was eating my brunch now (everybody does that nothing unusual), I tried to map the food eating actions and it sort of puzzled me..

there are lot of complicated actions brain does within no time, I agree and this research by itself is voluminous but wen I swallowed the food I realise the food in the food pipe descends with very great speed which is least controlled by the voluntary action control system of brain (general terms), I tried to slow down but I couldn't, I was wondering why

may be the descending velocity gained by the food is enhanced by the gravitational pull to a certain extent?
may be the role of gravity is not there at all? (possible?)
if yes how is the respiratory system works with ease releasing the CO2 outside (comparing with respect to the gravity only )
how does heart pumps blood higher to its level of location and against the gravity?
why is that we dont feel the difficulty these against gravity mechanisms inside our body.

I am trying to think everything in terms of basic physics and mechanics.

If these are understood we have a huge application in terms of aerodynamics and space science etc and what not.

part 2

the voluntary actions just as walking, learning etc are intensely studied I dont know how far the involuntary actions such as digestion, respiration, reproduction, circulation is done from neuroscience point of view .. Can some one light me in this?

Is societal behaviour evolutionary?

2011-01-13T01:03:00.000-08:00

Hi all,
Actually now I am watching a documentary named "Why we love" in discovery channel. There I realise the psychology of love. How evolutionary it is. But if I see all the love, lust, sex factors to be evolutionary from chimp, gorilla and that of man's (In detail watch discovery) how is that brain also has factors such as shyness, complex cognitive aspects such as shame, guilt, tricks, cheating, betray etc ... Are these evolutionary ? This question arises because I haven t seen any female animal being shy or guilt doing sex or love, though cheating is nature s way to survive still only with purpose it does and not like humans when we dont know why we do this.

any comments?

holistic video might be a good approach

2011-01-07T17:38:00.000-08:00

After a very long time I am updating my blog .. :)
When I use to read papers and journals for any topic , I use to find lots of misleading words, contradicting sentences confusing english even in top journals, yet it is a practice for your research and you gain experience to take what you want from those papers and distil others . I thought why is that only some topics or superficial school topics are only in videos and there are lot of youtube videos individually telling only research without intergrating. For eg. consider we are trying to learn the aplysia s feeding mechanism, there we might find inidvidual electrophysiological recordings, individual molecular mechanisms involved in it etc etc as videos, but we dont find the bridge between them. There should be some professional shooting company which sponsors researchers and other youtube videos wherein they try to integrate and help young researchers to understand even more better and reduce the misleading approaches of papers and their sentences in it. I call it a holistic approach and this might improve the interest in research more rapidly and effectively than any other means.
Any comments?

memory of survival and threats

2010-12-27T06:38:00.000-08:00

Hi all,

We all know each and every organism has its own strategy to survive. Consider a deer is attacked by a lion, the instincts the brain creates by both the lion and deer and the memories it has , the molecular mechanism involved. I would like to know what would be the fundamental mechanism involved and which part of brain is involved which co ordinates the excape mechanism, the past experience (memory) and instinct.

wat makes an ant an ant and not elephant in size?

2010-12-22T06:11:00.000-08:00

Hi all,
Today when I was having a walk in nearby park . I could see lot of ants with lot of sizes. We can say all of same species but different age but those size was approximately maintaining within the same age. This made me wonder. We all know genes control cell growth and lot of proteins concentration gradient control within the growth . I am wondering what makes the genes to turn on and off ?

why is that there is no conscious involuntary actions?

2010-12-21T07:28:00.000-08:00

Hi all,
We have been thought that involuntary actions like heart beat and lungs are done not consciously that is we dont feel all the time when you are breathing unless or until you have a nose block or atleast a common cold. My question is how does brain maintains this involuntary actions not registering in our conscious mind?

sixth sense - tool for neuro imaging?

2010-12-20T07:01:00.000-08:00

http://www.youtube.com/watch?v=fQEHtvNsfKE video on sixth sense by Pranav mistry fascinated me . I was just wondering to just use the same technology in imaging live samples or in particular the 3D complex brain structure can be imaged and the information from the brain can be extracted and analysed . I basically see a bright future to this technology in the field of imaging and doing quality research. Consider we have a sample being viewed we can easily analyse the sample immediately and see the quality of the research you have done and the imaging.

any other ideas and comments?

can the same site of repression be site of enhancement?

2010-12-19T08:37:00.000-08:00

Well,
I remember me doing my masters project in the non coding regions of mRNA. It started like this.
I want to see the length of the poly AA region in 3'UTRs of an mRNA of a certain hox gene in drosophila. These hox genes are very tricky because they themself being transcription factors, regulate their own expression by inhibiting and being inhibited by their family members itself during patterning the embryo. Can also called name giving genes as they define the regions being expressed. They are also regulated by non coding RNA s as well . Hmm!! very complex :(
To make it even complex :
I was doing my project in the direction of these regions (poly A tails) being used for down regulation of mRNA to be translated.
When I was listening to Prof Simon Morley, University of Sussex Talk about 3'UTR being used for up regulation as well, I was wondering what makes the site doing two contractory functions.

One possibility being different protein binding action leading to different function. Is there any other hypothesis?

CNS, gap junctions and chakra meditation

2010-12-17T20:04:00.000-08:00

The paper (Neurobiology of Chakras and Prayer

with Richard W. Maxwell, “The Physiological Foundation of Yoga Chakra Expression”;

and Ruth Stanley, “Types of Prayer, Heart Rate Variability, and Innate Healing”

THE PHYSIOLOGICAL FOUNDATION OF YOGA

CHAKRA EXPRESSION

by Richard W. Maxwell) interested me.

According to this paper the electrical synapses done by the gap junction may have concentrated in certain regions located in each level with the endocrine system together constitute the chakras in our body. These chakras have shown increased CNS function when activated and thus yogic practice is done through these. Fine, if chakras are the concentrated gap junction proteins what is kundalini shakthi???

This should be the electrical conductance which is activated at the base of spine and there may lie a balanced electrical conductivity from afferent and efferent nerves ?

Well this paper proposes " the kundalini is, in part, a

subjective representation of state changes among polar molecules within a

channel in the CNS rising from the filum terminale to the brain.In this framework, that channel (sushumna,

or sus’umna’ in Roman Sanskrit) is a column of gap junction linked cells

whose gap junctions open as the kundalini rises. The broader aspects of

the sushumna are a product of the glial syncytium extending through the

whole volume of the spine and brain. Meditation functions to increase the

prevalence of gap junctions and integrate compartments within the glial

network, ultimately allowing a full electrical unification of the spine and

brain." This sushumna (the CNS channel in the spinal cord also called brahmanadi) has great role in development of neural tube wherein gap junctions in it plays an important role.

even acupuncture is shown to concentrate gap junction proteins like connexins and pannexins but in less volume and area compared with the chakras with electrical conductance achieved.

The paper concludes saying,

"Physical systems related to a chakra have three

main aspects: a physical base that exists in the dorsal CNS, a concentration

point that is activating to that physical base, and influence of that physical

base over the activity of particular glandular secretions that have the potential

to bias mental function. With appropriate forms of concentration,

gap junction linkages in autonomic plexuses and elsewhere, typically subordinated

to chemical synaptic activity, may become activated (or regenerated)

and result in stimulation of important sites in the dorsal CNS.

Additionally, control over glandular functions may be susceptible to modulation

by gap junction mechanisms, presumably through autonomic nerves

Richard W. Maxwell 819

associated with these dorsal CNS sites. Identification of gap junctions within

the nervous system has had difficulties, and it is not likely to be easy to

find the proposed chakra centers within the CNS in animals or humans.

Functional magnetic resonance imaging (fMRI), or perhaps new technologies

such as functional near-infra-red spectrometry (fNIRS), together with

more refined electrophysiology could potentially yield signs of this underlying

physiology. If gap junctions are associated with chakra function, some

type of electrical signature should be present that could be identified. At

least one researcher has claimed to have identified electrophysiological signs

of chakra activity (Motoyama 1981). However, there is no evidence that

this work has been subjected to any peer review process."

Will musical notes affect you?

2010-12-16T22:57:00.000-08:00

I have seen a holistic effect of music on us, some say relaxing but its more than psychology alone. Each and every music affects us differently, right from pop, jazz to eastern music such as classical hindustani and carnatic music. though the basic notes for all the music is same, yet there seems different varieties, choices etc. According to me music defines you and shapes your social character. How? We all know animals and plants respond to music as well. Right from the beats to the notes in it. The music through our olfactory system or auditory cortex, creates an impact on us. This music is somehow co related to vision that is what you see is as well recorded. Though we have lots of research on music that is Western classical music s impact on psychoneuro aspect we have little knowledge about the travelling notes which is basis of the eastern music and the molecular and genetic changes it gives. I basically think music in general affect the neural activity of neural cell cycle epigenetically. Can someone enlighten me with this topic?

http://network.nature.com/groups/G5FCF230C/forum/topics/8678
check it its even nature journals

Musical Scientists forum :)

Is camouflage optical illusion ?

2010-12-16T06:16:00.000-08:00

I remember me taking optical illusion in my masters assignment and scoring very low. reason being camouflage a natural phenomenon and not an optical illusion.. I am still not satisfied people say its not an optical illusion. misinterpretation of the sensory input from the sensory organs is optical illusion. Nature uses this phenomenon in the form of camouflage and creates species through the concept of evolution. But why is this concept not considered an optical illusion.

scientific reasons plz

"love" from neuroscience perspective

2010-12-15T10:46:00.000-08:00

well a general start but now with specific topics ..
the thing which haunted me the most is love...
being in love and been love is unique..
99.99% it starts as friendship but we realize it is more than friendship when we see in the opposite one..
but lots think it is hormonal true.. but how?
the basis is that , brain repeats itself universally yet uniquely.. i see almost everyone cross this lake of love but each and everyone cross it differently.. what makes people think uniquely is the question..
well genetically it is possible to think uniquely.. the reason is we all know genes vary with person to person but those genes are same in the case of twins but the thing which makes these persons vary is epigenetics.. the gene code is the same while the histone modification is different.
research tells us it plays a great role in memory , learning etc etc..
these things are greatly affected by hormones in some way..
so naturally love is a way hormonal yet very powerful than just hormonal y so?
love is a good feeling or impulse created and registered as a simple attraction yet it grows as and wen this impulse gets strong and connected.. a thought tangle is created between them no matter how far they are but it does all sorts of mystical things practically but its nothing but concentrating once thought being practised scientifically..
love is one such weapon which controls unconscious mind consciously.. which makes it strong and grows parasitically over time...

universal love or loving each and everything is the next stage wherein u love even the most saddest thing or hated thing anything for that matter..
real love towards a person can lead u to this state which is seen as a person turned philosophical (in normal persons terms) in specific in the case of love failure..
but actually it is not failured love which makes the person see love universally but it is the opposite that is the strong impulse in their love towards that person..
understanding love is mystical provided u really undertsand the person s thoughts ..

I want someone to explain me what love is more scientifically :)